Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200862 | 0.79 | TSHR (0.63) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL23777037 | 0.76 | TSHR (0.59) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL601643 | 0.76 | TSHR (0.59) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL11474021 | 0.74 | TSHR (0.57) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL4445835 | 0.74 | TSHR (0.57) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL27926613 | 0.74 | TSHR (0.57) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL12977332 | 0.74 | TSHR (0.57) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL11505949 | 0.73 | TSHR (0.55) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL29134108 | 0.73 | TSHR (0.55) | TSHRTP53LMNAF2PDCD1 | |
| SCHEMBL9615408 | 0.73 | TSHR (0.55) | TSHRTP53LMNAF2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |