Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205077 | 0.89 | RAF1 (0.77) | RAF1BRAF | |
| SCHEMBL16037859 | 0.89 | RAF1 (1.00) | RAF1BRAF | |
| SCHEMBL28024747 | 0.86 | RAF1 (0.80) | RAF1BRAF | |
| SCHEMBL28821315 | 0.86 | RAF1 (0.70) | RAF1BRAF | |
| SCHEMBL16035248 | 0.86 | RAF1 (1.00) | RAF1BRAF | |
| SCHEMBL28025228 | 0.85 | RAF1 (0.69) | RAF1BRAF | |
| SCHEMBL28610840 | 0.84 | RAF1 (0.91) | RAF1BRAF | |
| SCHEMBL28619677 | 0.84 | RAF1 (0.91) | RAF1BRAF | |
| SCHEMBL16035973 | 0.84 | RAF1 (0.89) | RAF1BRAF | |
| SCHEMBL16035976 | 0.84 | RAF1 (1.00) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108467369-A | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | 诺华股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105143209-B | Biaryl amide compounds as kinase inhibitors | 诺华股份有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |