Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577125 | 0.86 | MAOB (0.55) | MAOBPARP15PARP10PARP14MAPT | |
| SCHEMBL17804382 | 0.81 | MAOB (0.65) | MAOBPARP15PARP10PARP14MEN1 | |
| SCHEMBL13793731 | 0.80 | MRGPRX4 (0.48) | MAOBMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8622099 | 0.78 | MAOB (0.47) | MAOBPARP15PARP10PARP14MAPT | |
| SCHEMBL12423201 | 0.77 | MAOB (0.69) | MAOBPARP15PARP10PARP14SCN9A | |
| SCHEMBL5090324 | 0.77 | MAOB (0.59) | MAOBPARP15PARP10PARP14PTPN1 | |
| SCHEMBL21083437 | 0.77 | MAOB (0.55) | MAOBPARP15PARP10PARP14L3MBTL1 | |
| SCHEMBL12973310 | 0.77 | MAOB (0.55) | MAOBPARP15PARP10PARP14PTPN1 | |
| SCHEMBL12894367 | 0.76 | HTR2A (0.43) | MAOBMAPTL3MBTL1SCN9ASCN5A | |
| SCHEMBL363646 | 0.76 | SCN9A (0.51) | MAPTL3MBTL1SCN9ASCN5APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104797555-B | N-substituted benzamides and methods of use thereof | 基因泰克公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105492430-A | Substituted benzoxazoles and methods of use thereof | GENENTECH INC | 2016-04-13 | — | — | CN | disclosed |
| CN-104797555-A | N-substituted benzamides and methods of use thereof | GENENTECH INC | 2015-07-22 | — | — | CN | disclosed |