SCHEMBL21083437

SCHEMBL21083437

Cc1ccc(OCc2ccccc2F)cc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.55
PARP15 Q460N3 3/20 0.55
PARP10 Q53GL7 3/20 0.55
PARP14 Q460N5 1/20 0.51
RAB9A P51151 2/20 0.51
KMT2A Q03164 1/20 0.51
NPC1 O15118 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ESR1 P03372 1/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
MAPK1 P28482 1/20 0.47
ESR2 Q92731 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
AR P10275 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8808591 0.86 MAOB (0.55) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL21084323 0.83 MAOB (0.49) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL20085194 0.82 MAOB (0.51) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL13794698 0.81 TDP1 (0.51) MAOBRAB9AKMT2ANPC1ESR1
SCHEMBL10397561 0.81 MAOB (0.60) MAOBPARP15PARP10PARP14HPD
SCHEMBL13320309 0.81 MAOB (0.65) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL38655920 0.81 MAOB (0.65) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL12443168 0.81 PTPN1 (0.53) MAOBPARP15PARP10PARP14RAB9A
SCHEMBL8623315 0.80 POLB (0.47) MAOBRAB9AKMT2ANPC1SMN1; SMN2
SCHEMBL21084234 0.80 LMNA (0.57) MAOBPARP15PARP10PARP14RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3492461-A1 NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF Shanghai Yingli Pharmaceutical Co. Ltd. (CN) 2019-06-05 EP disclosed