Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1589841 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL1589895 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL10439343 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL10710633 | 0.81 | HDAC1 (0.42) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL7267182 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL4275739 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL10711343 | 0.80 | HDAC1 (0.41) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL10711338 | 0.80 | HDAC1 (0.41) | KDM4EALDH1A1GLAMAOACYP3A4 | |
| SCHEMBL10708787 | 0.79 | KCNK3 (0.46) | KDM4EALDH1A1GLAMAOAMAPT | |
| SCHEMBL10711339 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1GLAMAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153188-A | Fused ring analogues of anti-fibrotic agents | FIBROTECH THERAPEUTICS PTY LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-102574843-B | Fused ring analogs of anti-fibrotic agents | FIBROTECH THERAPEUTICS PTY LTD | 2015-06-17 | — | — | CN | disclosed |