Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.40 |
| ▸ | WNT3A | P56704 | 7/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397421 | 0.81 | CLK1 (0.46) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL577552 | 0.81 | CLK1 (0.46) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| Ethoxycarbonyl Group SCHEMBL27822093 | 0.81 | CTNNB1 (0.40) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| Oxirane SCHEMBL27706875 | 0.78 | ALK (0.44) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| Ethoxycarbonyl Group SCHEMBL27889131 | 0.76 | CTNNB1 (0.41) | CTNNB1WNT3A | |
| SCHEMBL28134281 | 0.75 | CLK1 (0.44) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL29791452 | 0.71 | MAPT (0.54) | DYRK1ADYRK1BRIPK1FABP6ERN1 | |
| SCHEMBL564862 | 0.71 | MAPT (0.54) | DYRK1ADYRK1BRIPK1FABP6ERN1 | |
| Ethoxycarbonyl Group SCHEMBL27323072 | 0.71 | CYP1A2 (0.43) | — | |
| Ethoxycarbonyl Group SCHEMBL27531572 | 0.69 | ITGB2 (0.52) | CTNNB1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102180856-B | One prepares the method for fluoro-3, the 4-dihydro-2 H-1-benzopyran-2-ethyl formates of 6- | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-102180856-B | One prepares the method for fluoro-3, the 4-dihydro-2 H-1-benzopyran-2-ethyl formates of 6- | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-102180855-B | A kind of method of purification of Nebivolol Intermediates | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-103709132-B | A kind of preparation method of Nebivolol Intermediates | JIANGSU BAJU PHARMACEUTICAL CO., LTD. (CN) | 2015-08-19 | — | — | CN | disclosed |