Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.46 |
| ▸ | WNT3A | P56704 | 5/20 | 0.46 |
| ▸ | FABP6 | P51161 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397421 | 1.00 | CLK1 (0.46) | CLK1DYRK1ADYRK1BALKCTNNB1 | |
| Oxirane SCHEMBL27706875 | 0.96 | ALK (0.44) | CLK1DYRK1ADYRK1BALKCTNNB1 | |
| SCHEMBL564862 | 0.88 | MAPT (0.54) | DYRK1ADYRK1BFABP6PRKCINPC1 | |
| SCHEMBL29791452 | 0.88 | MAPT (0.54) | DYRK1ADYRK1BFABP6PRKCINPC1 | |
| SCHEMBL3644639 | 0.84 | FABP6 (0.41) | ALKCTNNB1WNT3AFABP6RIPK1 | |
| SCHEMBL30665414 | 0.84 | FABP6 (0.41) | ALKCTNNB1WNT3AFABP6RIPK1 | |
| Ethoxycarbonyl Group SCHEMBL28025317 | 0.81 | CTNNB1 (0.40) | CLK1DYRK1ADYRK1BALKCTNNB1 | |
| SCHEMBL29692961 | 0.81 | FABP6 (0.39) | ALKCTNNB1FABP6PRKCINPC1 | |
| SCHEMBL30507863 | 0.77 | CTNNB1 (0.46) | CTNNB1WNT3AFABP6NPC1MAPT | |
| SCHEMBL23653205 | 0.76 | DYRK1A (0.46) | CLK1DYRK1ADYRK1BCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-120058664-A | Melatonin receptor agonist, and preparation method and application thereof | 宜昌市中心人民医院(三峡大学第一临床医学院、三峡大学附属中心人民医院) | 2025-05-30 | — | — | CN | disclosed |
| CN-120026004-A | Lipase mutant and application thereof in preparation of nebivolol intermediate | 尚科生物医药（上海）有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | disclosed |
| CN-114075141-B | Opioid receptor \"bias\" ligand, preparation method and medical application thereof | 上海致根医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118373795-A | Continuous flow preparation process of chloroketone | 济南立德医药技术有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-114149956-B | Escherichia coli genetically engineered bacterium for expressing esterase EstR and application thereof | 华东理工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114214261-B | Escherichia coli genetically engineered bacterium for expressing esterase EstS and application thereof | 华东理工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114150036-B | Continuous biphasic batch resolution process for preparing optically pure 6-fluoro-chroman-2-carboxylic acid | 华东理工大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-117051052-A | Method for asymmetrically synthesizing NEB-8 by using ketoreductase MrADH | 江南大学 | 2023-11-14 | — | — | CN | disclosed |
| EP-0109232-B1 | SORBINAL BY OPTICAL RESOLUTION OF PRECURSOR 6-FLURO-4-UREIDOCHROMAN-4-CARBOXYLIC ACID | PFIZER INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0111387-B1 | REGENERATION OF 6-FLUORO-4-CHROMANONE FROM BY-PRODUCTS IN THE SYNTHESIS OF SORBINIL | PFIZER INC. (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4565820-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-4528387-A | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0111387-A1 | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| EP-0109232-A1 | Sorbinal by optical resolution of precursor 6-fluro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4435578-A | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |
| US-4431828-A | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4431810-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4342771-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1982-08-03 | — | — | US | disclosed |