SCHEMBL28025334

SCHEMBL28025334

Cc1cc([SiH3])ccc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8222458 0.75
SCHEMBL2000010 0.74
SCHEMBL29387276 0.72
SCHEMBL29696046 0.72 HSD17B1 (0.68)
SCHEMBL29429121 0.72 HSD17B1 (0.68)
Methylhydroquinone SCHEMBL10426478 0.72 TP53 (0.62)
SCHEMBL92167 0.72
SCHEMBL272034 0.72 HSD17B1 (0.68)
Methylhydroquinone SCHEMBL29364957 0.72
SCHEMBL26979937 0.72 HSD17B1 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104817581-A Silicon-containing diphenol and preparation method thereof UNIV QUZHOU 2015-08-05 CN disclosed