SCHEMBL28025375

SCHEMBL28025375

C=CC(=O)OC(CC)[SiH](C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.39
HPGD P15428 1/20 0.38
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 4/20 0.33
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29018512 0.86 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28030112 0.85 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28131009 0.83 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9546118 0.83 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8093319 0.82 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29057324 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL139741 0.81 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28074174 0.80 TSHR (0.34) TSHRHPGD
SCHEMBL143214 0.79 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9860771 0.79 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107226907-B The method and product of a kind of anhydrous synthesizing organo-silicon oxygen alkane resin and application 广东标美硅氟新材料有限公司 2019-04-26 CN claimed
CN-107226907-A A kind of method of anhydrous synthesizing organo-silicon oxygen alkane resin and product and application 广东标美硅氟新材料有限公司 2017-10-03 CN claimed
CN-107151426-A A kind of fiberglass reinforced lactic acid composite material and its preparation method and application 黑龙江鑫达企业集团有限公司 2017-09-12 CN claimed
CN-104774437-B A kind of carbon fiber enhancement polylactic acid composite and its preparation method and application 北京汽车股份有限公司 2017-07-04 CN claimed
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN claimed
CN-107226907-B The method and product of a kind of anhydrous synthesizing organo-silicon oxygen alkane resin and application 广东标美硅氟新材料有限公司 2019-04-26 CN disclosed
CN-107226907-A A kind of method of anhydrous synthesizing organo-silicon oxygen alkane resin and product and application 广东标美硅氟新材料有限公司 2017-10-03 CN disclosed
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN disclosed