Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025375 | 0.85 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3750794 | 0.84 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL193209 | 0.82 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL2853098 | 0.81 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8007977 | 0.80 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL9545994 | 0.76 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL544590 | 0.76 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL29018512 | 0.76 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28071076 | 0.75 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL865527 | 0.75 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141427-A | A kind of photochromic composition and its application | 无锡创彩光学材料有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-105308074-A | Photochromic curable composition | TOKUYAMA CORP | 2016-02-03 | — | — | CN | disclosed |
| CN-103703029-B | Photochromic curable composition | TOKUYAMA CORP. (JP) | 2016-01-06 | — | — | CN | disclosed |
| CN-104995281-A | Photochromic curable composition | TOKUYAMA CORP | 2015-10-21 | — | — | CN | disclosed |