SCHEMBL28025527

SCHEMBL28025527

CC(C(=O)O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1O.OCC(CO)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 3/20 0.50
CYP1A2 P05177 2/20 0.50
TSHR P16473 2/20 0.50
NR5A2 O00482 1/20 0.39
NR5A1 Q13285 1/20 0.39
GLRA3 O75311 1/20 0.38
GLRB P48167 1/20 0.38
HSP90AA1 P07900 1/20 0.37
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
LMNA P02545 2/20 0.36
GABBR2 O75899 2/20 0.36
GABBR1 Q9UBS5 2/20 0.36
MEN1 O00255 1/20 0.36
GMNN O75496 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7720160 0.91 CYP3A4 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Methane SCHEMBL8854369 0.90 CYP3A4 (0.52) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Hydrazine SCHEMBL28202215 0.88 CYP3A4 (0.51) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
E968 SCHEMBL30522296 0.88 CYP3A4 (0.49) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Allyl Alcohol SCHEMBL28219123 0.86 CYP1A2 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL27993102 0.85 CYP2C9 (0.52) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL28294460 0.85 CYP3A4 (0.44) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL28033950 0.84 CYP3A4 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Cetostearyl Alcohol SCHEMBL28220384 0.83 CYP1A2 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL28013375 0.82 AKR1C3 (0.42) CYP3A4CYP2C9CYP2C19CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627623-A A kind of low temperature resistant polyvinyl chloride soft goods composition and preparation method thereof 中国石油化工股份有限公司 2019-04-16 CN claimed
CN-105219006-A Automotive line halogen-free flameproof heat-resisting weather-proof polypropylene nano-composite insulating material and preparation technology thereof UNIV TONGJI 2016-01-06 CN claimed
CN-105199167-A Environment-friendly high and low temperature resistant and oil resistant flame-retardant nano-composite thermoplastic elastomer and preparation process thereof CHANGSHU INST TECHNOLOGY 2015-12-30 CN claimed
CN-105153621-A Anti-pre-crosslinking rapid-solidification low-smoke zero-halogen flame-retardant silane crosslinking nano-modified polyolefin composition CHANGSHU INST TECHNOLOGY 2015-12-16 CN claimed
CN-107501795-B Low temperature resistant polyvinyl chloride soft goods composition and preparation method thereof 淄博职业学院 2019-10-01 CN disclosed
CN-109627623-A A kind of low temperature resistant polyvinyl chloride soft goods composition and preparation method thereof 中国石油化工股份有限公司 2019-04-16 CN disclosed
CN-107501795-A Low temperature resistant polyvinyl chloride soft goods composition and preparation method thereof 淄博职业学院 2017-12-22 CN disclosed
CN-105219006-A Automotive line halogen-free flameproof heat-resisting weather-proof polypropylene nano-composite insulating material and preparation technology thereof UNIV TONGJI 2016-01-06 CN disclosed
CN-105199167-A Environment-friendly high and low temperature resistant and oil resistant flame-retardant nano-composite thermoplastic elastomer and preparation process thereof CHANGSHU INST TECHNOLOGY 2015-12-30 CN disclosed
CN-105153621-A Anti-pre-crosslinking rapid-solidification low-smoke zero-halogen flame-retardant silane crosslinking nano-modified polyolefin composition CHANGSHU INST TECHNOLOGY 2015-12-16 CN disclosed