SCHEMBL28294460

SCHEMBL28294460

CC(C(=O)O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1O.CC(C)CCCCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
TSHR P16473 1/20 0.44
NR5A2 O00482 1/20 0.37
NR5A1 Q13285 1/20 0.37
VCAM1 P19320 2/20 0.34
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
ALOX5 P09917 3/20 0.32
PTGS2 P35354 3/20 0.32
PTGS1 P23219 2/20 0.32
KCNH2 Q12809 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetostearyl Alcohol SCHEMBL28220384 0.89 CYP1A2 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL28025527 0.85 CYP3A4 (0.50) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL7720160 0.84 CYP3A4 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL27993102 0.84 CYP2C9 (0.52) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Methane SCHEMBL8854369 0.83 CYP3A4 (0.52) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Hydrazine SCHEMBL28202215 0.82 CYP3A4 (0.51) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
E968 SCHEMBL30522296 0.81 CYP3A4 (0.49) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL28034637 0.81 CYP3A4 (0.41) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
Allyl Alcohol SCHEMBL28219123 0.80 CYP1A2 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2TSHR
SCHEMBL27949727 0.79 NR1H4 (0.37) CYP3A4CYP2C9CYP2C19CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762490-A A kind of heat-insulated PVB film and preparation method thereof 长春工业大学 2019-05-17 CN claimed
CN-109762490-A A kind of heat-insulated PVB film and preparation method thereof 长春工业大学 2019-05-17 CN disclosed