Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025617 | 1.00 | MAPK1 (0.51) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL15221118 | 0.86 | MAPK1 (0.52) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL1136065 | 0.86 | MAPK1 (0.52) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL14830273 | 0.86 | MAPK1 (0.52) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL16416468 | 0.86 | MAPK1 (0.52) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL1136066 | 0.86 | MAPK1 (0.52) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL498073 | 0.85 | MAPK1 (0.51) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL14838637 | 0.85 | MAPK1 (0.51) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL78371 | 0.85 | MAPK1 (0.51) | MAPK1HPGDTSHRF10LMNA | |
| SCHEMBL469776 | 0.85 | MAPK1 (0.51) | MAPK1HPGDTSHRF10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817550-A | Preparation method of rivaroxaban | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2015-08-05 | — | — | CN | disclosed |