Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025807 | 1.00 | P4HTM (0.47) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL5649401 | 0.82 | KMT2A (0.55) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL711104 | 0.82 | KMT2A (0.55) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL287558 | 0.79 | P4HTM (0.53) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL17495670 | 0.77 | SIRT6 (0.42) | KDM4EL3MBTL1MAPK1GABRA1GABRG2 | |
| SCHEMBL18401863 | 0.77 | SIRT6 (0.42) | KDM4EL3MBTL1MAPK1GABRA1GABRG2 | |
| SCHEMBL17162305 | 0.76 | P4HTM (0.54) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL29488317 | 0.76 | P4HTM (0.53) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL2300999 | 0.76 | P4HTM (0.53) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 | |
| SCHEMBL17520868 | 0.75 | P4HTM (0.49) | P4HTMKDM4EL3MBTL1MAPK1P4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |