Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15814919 | 0.98 | KDM4E (0.46) | KDM4EHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL27999787 | 0.93 | KDM4E (0.41) | KDM4EHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL2964294 | 0.85 | CYP2A6 (0.44) | KDM4EKDM1ACYP1A2CYP2A6 | |
| SCHEMBL7849802 | 0.85 | KDM4E (0.41) | KDM4EHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL2971420 | 0.84 | CYP2A6 (0.43) | KDM4EKDM1ACYP1A2CYP2A6 | |
| SCHEMBL27460809 | 0.81 | HTR2A (0.40) | KDM4EHTR2CHTR2BSLC6A2SLC6A3 | |
| SCHEMBL2966222 | 0.81 | CYP2A6 (0.47) | KDM4EHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL2958359 | 0.81 | CYP2A6 (0.47) | KDM4EHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL6874082 | 0.81 | CYP2A6 (0.33) | KDM4ECYP2A6 | |
| SCHEMBL2967629 | 0.79 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822697-A | Bridged metallocene compounds, catalyst systems and polymerization processes using the same | EXXONMOBIL CHEM PATENTS INC | 2015-08-05 | — | — | CN | disclosed |