Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124279 | 0.77 | OPRM1 (0.44) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL410055 | 0.77 | OPRM1 (0.44) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7178967 | 0.77 | GRIN2D (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7174207 | 0.77 | GRIN2D (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7174206 | 0.77 | GRIN2D (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7130225 | 0.77 | GRIN2D (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24821526 | 0.74 | OPRM1 (0.44) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL599176 | 0.74 | KDM1A (0.47) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL599175 | 0.74 | KDM1A (0.47) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22052004 | 0.74 | OPRM1 (0.42) | OPRM1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755473-A | 2,3-benzodiazepines | Bayer Pharma AG | 2015-07-01 | — | — | CN | disclosed |