Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331745 | 0.91 | HRH3 (0.56) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| Hydrochloric Acid SCHEMBL2333142 | 0.90 | HRH3 (0.55) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL2831968 | 0.85 | HRH3 (0.50) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL2333546 | 0.82 | HRH3 (0.47) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL3409607 | 0.80 | ALDH1A1 (0.46) | HRH3 | |
| SCHEMBL28026517 | 0.79 | KDM4E (0.45) | HRH3 | |
| SCHEMBL3404217 | 0.79 | HRH3 (0.44) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL3410705 | 0.78 | HRH3 (0.43) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL3403655 | 0.78 | HRH3 (0.43) | HRH3SIGMAR1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL3409858 | 0.77 | HSD17B10 (0.44) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015683-B | The indole derivatives replaced | GRUNENTHAL GMBH (DE) | 2015-08-05 | — | — | CN | claimed |
| CN-102015683-B | The indole derivatives replaced | GRUNENTHAL GMBH (DE) | 2015-08-05 | — | — | CN | disclosed |