Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30315706 | 0.79 | MAPT (0.66) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3139823 | 0.79 | MAPT (0.66) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29427468 | 0.78 | MIF (0.76) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4780298 | 0.77 | MIF (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4780542 | 0.76 | CA12 (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4798725 | 0.76 | CSNK2A1 (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31017575 | 0.76 | MEN1 (0.62) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16291610 | 0.76 | KDM4E (0.56) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16291613 | 0.76 | KDM4E (0.56) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28004008 | 0.75 | MEN1 (0.71) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829608-A | Coumarin-thiazole-indolone compounds, and preparation method and application thereof | UNIV JISHOU | 2015-08-12 | — | — | CN | disclosed |