Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780542 | 0.90 | CA12 (0.61) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL4780298 | 0.89 | MIF (0.53) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL4784287 | 0.84 | CA12 (0.51) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL4798176 | 0.80 | GRM1 (0.55) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3345136 | 0.77 | MAPT (0.50) | CSNK2A1CA12CA9RAB9ANPC1 | |
| SCHEMBL28026164 | 0.76 | MAPT (0.55) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL3338338 | 0.76 | CA12 (0.88) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL4800674 | 0.75 | GRM1 (0.57) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29427517 | 0.74 | MIF (0.70) | CSNK2A1CA12CA9MEN1KMT2A | |
| SCHEMBL4797456 | 0.74 | GRM1 (0.48) | CSNK2A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | claimed |