Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31730773 | 0.90 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL9575455 | 0.90 | KDM4E (0.80) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL14855680 | 0.87 | KDM4E (0.76) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL29028434 | 0.86 | KDM4E (0.70) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL14855798 | 0.84 | SMN1; SMN2 (0.75) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL14855679 | 0.83 | POLB (0.72) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL14856210 | 0.83 | KDM4E (0.69) | KDM4ELMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL14128773 | 0.82 | NPC1 (0.83) | KDM4ESMN1; SMN2POLBTDP1ALDH1A1 | |
| SCHEMBL16330055 | 0.80 | POLB (0.72) | SMN1; SMN2POLBTP53HPGDMAPK1 | |
| SCHEMBL15186932 | 0.80 | KDM4E (0.65) | KDM4ELMNASMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104745675-A | Medicament designed pocket of ornithine decarboxylase and application of medicament designed pocket | UNIV CHINA THREE GORGES CTGU | 2015-07-01 | — | — | CN | claimed |