SCHEMBL28026289

SCHEMBL28026289

CCC(C=O)Cc1c[nH]nc1C(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28896740 0.78
SCHEMBL27925554 0.77
SCHEMBL28198301 0.70
SCHEMBL27380920 0.69
SCHEMBL2599238 0.67
SCHEMBL27787853 0.67 PTGS2 (0.36) TSHR
SCHEMBL27774050 0.61
SCHEMBL17928454 0.61 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL17928453 0.61 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL19809939 0.61 HMGCR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104945325-B A kind of preparation method of pyrazole carboxylic acid derivant 浙江永太科技股份有限公司 2017-04-05 CN disclosed
CN-104945387-B Intermediate for preparing pyrazol formic acid derivative 浙江永太科技股份有限公司 2017-03-22 CN disclosed
CN-104945325-A Preparation method for pyrazolecarboxylic acid derivative ZHEJIANG YONGTAI TECHNOLOGY CO LTD 2015-09-30 CN disclosed
CN-104945387-A Intermediate for preparing pyrazol formic acid derivative ZHEJIANG YONGTAI TECHNOLOGY CO LTD 2015-09-30 CN disclosed