⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026350 | 1.00 | — | — | |
| SCHEMBL28026324 | 1.00 | — | — | |
| SCHEMBL7524063 | 0.84 | FFAR2 (0.37) | — | |
| SCHEMBL10049702 | 0.82 | — | — | |
| SCHEMBL6848836 | 0.78 | — | — | |
| SCHEMBL7412590 | 0.77 | — | — | |
| SCHEMBL7349104 | 0.74 | — | — | |
| SCHEMBL2846695 | 0.74 | — | — | |
| SCHEMBL11308102 | 0.74 | HPGD (0.32) | — | |
| SCHEMBL18609320 | 0.72 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-B | It can be used as the acid amides of pyridine 2 of CB2 activators | 霍夫曼-拉罗奇有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | claimed |
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |