Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139376 | 0.87 | KRAS (0.52) | LMNAKRASALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL28026377 | 0.85 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AELANE | |
| SCHEMBL15167352 | 0.84 | LMNA (0.62) | LMNAALDH1A1SMN1; SMN2IDO1MEN1 | |
| SCHEMBL28025825 | 0.82 | NR4A2 (0.55) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28025826 | 0.81 | MAPT (0.53) | LMNAALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL28026400 | 0.81 | LMNA (0.50) | LMNAKRASALDH1A1IDO1MAPK1 | |
| SCHEMBL14631424 | 0.76 | KMT2A (0.55) | LMNAIDO1MEN1KMT2ANR4A2 | |
| SCHEMBL22450675 | 0.75 | KMT2A (0.38) | LMNAIDO1MEN1KMT2ANR4A2 | |
| SCHEMBL20380252 | 0.75 | NR4A2 (0.48) | KRASALDH1A1SMN1; SMN2IDO1MEN1 | |
| SCHEMBL19202547 | 0.74 | NR4A2 (0.64) | LMNAKRASALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945303-A | Preparation method of 3-alkenyl indole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |