Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Etiracetam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | CA12 | O43570 | 1/20 | 0.97 |
| ▸ | CA1 | P00915 | 1/20 | 0.97 |
| ▸ | CA2 | P00918 | 1/20 | 0.97 |
| ▸ | CA3 | P07451 | 1/20 | 0.97 |
| ▸ | CA4 | P22748 | 1/20 | 0.97 |
| ▸ | CA6 | P23280 | 1/20 | 0.97 |
| ▸ | CA5A | P35218 | 1/20 | 0.97 |
| ▸ | CA7 | P43166 | 1/20 | 0.97 |
| ▸ | CA9 | Q16790 | 1/20 | 0.97 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.97 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.97 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.97 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etiracetam SCHEMBL373194 | 0.98 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL118843 | 0.98 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL5072485 | 0.98 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levitiracetam SCHEMBL61493 | 0.98 | LMNA (1.00) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL17372720 | 0.97 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL28457423 | 0.97 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Etiracetam SCHEMBL22031970 | 0.97 | LMNA (0.97) | LMNACA12CA1CA2CA3 | |
| Levetiracetam SCHEMBL6073150 | 0.93 | LMNA (0.90) | LMNACA12CA1CA2CA3 | |
| SCHEMBL660679 | 0.93 | LMNA (0.90) | LMNACA12CA1CA2CA3 | |
| SCHEMBL661433 | 0.92 | LMNA (0.87) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751983-A | HER3 antigen binding molecules | 蜂鸟生物科技私人有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-105477012-B | A kind of Levetiracetam sodium chloride injection composition and preparation method thereof | 河北仁合益康药业有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-107913245-A | A kind of preparation method of Levetiracetam sodium chloride injection | 北京阜康仁生物制药科技有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104860863-B | Levetiracetam and the pharmaceutical composition containing it | 惠州信立泰药业有限公司 | 2017-06-20 | — | — | CN | disclosed |
| CN-105412007-A | Levetiracetam-sodium chloride injection compound and preparation method thereof | Hebei renhe yikang pharmaceutical co ltd | 2016-03-23 | — | — | CN | disclosed |
| CN-104860863-A | High-purity levetiracetam and pharmaceutical composition comprising high-purity levetiracetam | HUIZHOU XINLITAI PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |