Methane

Methane

SCHEMBL28026804

C.C=CCNc1ccccn1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.56
CXCR4 P61073 1/20 0.53
FABP1 P07148 1/20 0.52
FABP6 P51161 1/20 0.52
CYP2C19 P33261 1/20 0.51
ALDH1A1 P00352 2/20 0.49
CYP1A2 P05177 1/20 0.49
HCAR3 P49019 1/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
CYP2D6 P10635 1/20 0.45
SUMO3 P55854 1/20 0.44
SUMO2 P61956 1/20 0.44
SUMO1 P63165 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPK10 P53779 1/20 0.44
GFER P55789 1/20 0.44
GAA P10253 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002291 0.98 SLC2A1 (0.58) SLC2A1CXCR4FABP1FABP6CYP2C19
SCHEMBL27688762 0.87 SLC2A1 (0.52) SLC2A1CXCR4FABP1FABP6CYP2C19
Hydrochlorthiazide SCHEMBL28080447 0.83 SLC2A1 (0.46) SLC2A1CXCR4FABP1FABP6CYP2C19
SCHEMBL9453409 0.78 CXCR4 (0.55) CXCR4FABP1FABP6CYP2C19ALDH1A1
SCHEMBL8915585 0.76 CXCR4 (0.52) CXCR4FABP1FABP6CYP2C19ALDH1A1
SCHEMBL8860852 0.76 CXCR4 (0.52) CXCR4FABP1FABP6CYP2C19ALDH1A1
SCHEMBL19030955 0.76 CXCR4 (0.52) CXCR4FABP1FABP6CYP2C19ALDH1A1
SCHEMBL7174094 0.75 SLC2A1 (0.46) SLC2A1CYP2C19ALDH1A1CYP1A2HCAR3
SCHEMBL1345287 0.75
SCHEMBL3265804 0.74 CYP1A2 (0.70) CXCR4FABP1FABP6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104826655-A Alkylamino pyridine catalyst taking active carbon as carrier and preparation method thereof UNIV FUJIAN AGRIC & FORESTRY 2015-08-12 CN disclosed