Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 4/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10020217 | 0.80 | GRM4 (0.64) | GRM4FFAR1GRM5 | |
| SCHEMBL3581835 | 0.76 | PIK3CA (0.44) | FFAR1ASIC3GRM5PIK3CAMTOR | |
| SCHEMBL2809759 | 0.74 | ERN1 (0.49) | ASIC3GRM5PIK3CAMTORPDK1 | |
| SCHEMBL4968126 | 0.74 | CYP3A4 (0.58) | FFAR1ASIC3PIK3CAMTORPDK1 | |
| SCHEMBL28421265 | 0.73 | PTGDR2 (0.47) | GRM4FFAR1GRM5 | |
| SCHEMBL4711036 | 0.73 | GRM5 (0.67) | GRM5 | |
| SCHEMBL26886953 | 0.73 | ASIC3 (0.44) | GRM4FFAR1ASIC3PIK3CAMTOR | |
| SCHEMBL31139969 | 0.72 | ASIC3 (0.49) | FFAR1ASIC3PIK3CAMTORPDK1 | |
| SCHEMBL708798 | 0.71 | FFAR1 (0.56) | GRM4FFAR1GRM5 | |
| SCHEMBL10020221 | 0.71 | FFAR1 (0.56) | GRM4FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829613-B | Diaryl-substituted pyrazolo ring derivative, preparation method thereof and application thereof in medical field | 赤峰蒙广生物科技有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-104829613-A | Diaryl-substituted pyrazolo ring derivative and preparation method thereof, and applications of diaryl-substituted pyrazolo ring derivative in medicine field | SHANGHAI ACEBRIGHT PHARMACEUTICALS GROUP CO LTD | 2015-08-12 | — | — | CN | disclosed |