Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027415 | 0.82 | BRD4 (0.43) | BRD4 | |
| SCHEMBL28027373 | 0.82 | BRD4 (0.39) | BRD4THRATHRB | |
| SCHEMBL28028059 | 0.82 | PRKCI (0.34) | — | |
| SCHEMBL28027381 | 0.74 | BRD4 (0.39) | BRD4 | |
| SCHEMBL28027980 | 0.73 | BRD4 (0.37) | BRD4 | |
| SCHEMBL28027450 | 0.70 | BRD4 (0.39) | BRD4 | |
| SCHEMBL23117766 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL3631132 | 0.66 | ALDH1A1 (0.42) | BRD4 | |
| SCHEMBL28028011 | 0.66 | BRD4 (0.41) | BRD4 | |
| SCHEMBL3631924 | 0.65 | BRD4 (0.41) | BRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |