Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404301 | 0.88 | MTNR1A (0.42) | MTNR1AMTNR1BELANEPPARGPPARA | |
| SCHEMBL10431848 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BPPARGPPARACYP1A2 | |
| SCHEMBL28364684 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BELANEPPARGPPARA | |
| SCHEMBL10600347 | 0.85 | TSHR (0.45) | MTNR1AMTNR1BELANEPPARGPPARA | |
| Ethylene Glycol SCHEMBL737599 | 0.81 | TSHR (0.41) | MTNR1AMTNR1BELANEPPARGPPARA | |
| SCHEMBL1405869 | 0.80 | MTNR1A (0.37) | MTNR1AMTNR1BELANEPPARGPPARA | |
| SCHEMBL17351289 | 0.79 | ELANE (0.45) | MTNR1AMTNR1BELANEPPARGPPARA | |
| SCHEMBL21370 | 0.79 | MTNR1A (0.45) | MTNR1AMTNR1BELANECYP1A2GAA | |
| SCHEMBL1405945 | 0.78 | MTNR1A (0.35) | MTNR1AMTNR1BELANEGAAMAPT | |
| SCHEMBL1524321 | 0.78 | MTNR1A (0.35) | MTNR1AMTNR1BELANEGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102225945-B | A kind of (methyl) vinylformic acid esterification oxazole heterocyclic boronic acids ester and its preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |