SCHEMBL28027732

SCHEMBL28027732

OCC1(Cc2ccccc2)OC(Cc2ccccc2)(Cc2ccccc2)OC1(CO)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
MAOA P21397 7/20 0.36
MAOB P27338 7/20 0.36
KDM1A O60341 5/20 0.34
CALM1 P0DP23 1/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1680265 0.73 TDP1 (0.43) TSHRTDP1MAOAMAOBKDM1A
SCHEMBL7402503 0.67 MAOA (0.48) MAOAMAOBKDM1A
SCHEMBL14778755 0.67 MAOA (0.43) MAOAMAOBKDM1ACALM1LMNA
SCHEMBL19809374 0.67 MAOA (0.39) TSHRMAOAMAOBKDM1ACALM1
SCHEMBL1680498 0.67 TDP1 (0.45) TSHRTDP1MAOAMAOBKDM1A
SCHEMBL13423060 0.66 MAOB (0.46) TSHRMAOAMAOBKDM1ACALM1
SCHEMBL14779625 0.66 MAOA (0.46) MAOAMAOBKDM1ACALM1LMNA
SCHEMBL9483827 0.65 TDP1 (0.39) TSHRTDP1MAOAMAOBKDM1A
SCHEMBL9384798 0.65 MAOA (0.42) TSHRTDP1MAOAMAOBKDM1A
SCHEMBL7434413 0.64 MAOA (0.39) TSHRTDP1MAOAMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844654-B A kind of quaternary salt compounds and preparation method thereof 昆明理工大学 2016-11-02 CN disclosed
CN-104844654-A Quaternary phosphonium salt compound and preparation method thereof UNIV KUNMING SCIENCE & TECHNOLOGY 2015-08-19 CN disclosed