Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anilinobenzamide SCHEMBL1318994 | 0.85 | SIRT2 (0.73) | SIRT2SIRT1FABP4MAPTALOX15 | |
| SCHEMBL15798173 | 0.82 | BRD4 (0.52) | BRD4SIRT2SIRT1CXCR2FABP4 | |
| SCHEMBL28274346 | 0.79 | BCAT2 (0.70) | BRD4SIRT2SIRT1CXCR2BCAT2 | |
| SCHEMBL210767 | 0.79 | BCAT2 (0.74) | SIRT1BCAT2MAPT | |
| SCHEMBL13363917 | 0.79 | MAPT (0.61) | BRD4CXCR2FABP4MAPTALOX15 | |
| SCHEMBL30514077 | 0.79 | BCAT2 (0.74) | SIRT1BCAT2MAPT | |
| SCHEMBL28027868 | 0.79 | BCAT2 (0.53) | SIRT2BCAT2MAPT | |
| SCHEMBL2723037 | 0.78 | SIRT2 (0.58) | BRD4SIRT2SIRT1CXCR2FABP4 | |
| SCHEMBL31252862 | 0.77 | CYP3A4 (0.74) | SIRT2BCAT2 | |
| SCHEMBL10984674 | 0.77 | SIRT2 (0.69) | SIRT2SIRT1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101503393-B | Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO.,LTD. (JP) | 2015-08-19 | — | — | CN | disclosed |
| CN-102596939-B | Compounds for organic light emitting diode emissive layers | NITTO DENKO CORP | 2014-08-13 | — | — | CN | disclosed |