Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | AADAC | P22760 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028581 | 0.88 | AR (0.50) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL5923538 | 0.87 | LMNA (0.54) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL15727592 | 0.86 | LMNA (0.52) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL28028086 | 0.80 | AR (0.50) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL23839646 | 0.79 | CNR2 (0.53) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL946269 | 0.79 | AR (0.52) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL382236 | 0.79 | AR (0.49) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL946271 | 0.79 | AR (0.52) | ARCYP3A4LMNACES2ABCB11 | |
| Hydrochloric Acid SCHEMBL381573 | 0.78 | AR (0.48) | ARCYP3A4LMNACES2ABCB11 | |
| SCHEMBL28222069 | 0.78 | AR (0.41) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884453-A | Anthelmintic compounds and compositions and methods of using the same | MERIAL LTD | 2015-09-02 | — | — | CN | disclosed |