Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400615 | 1.00 | KLK5 (0.53) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL16462573 | 0.96 | KLK5 (0.53) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL289669 | 0.96 | KLK5 (0.53) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL3836761 | 0.96 | KLK5 (0.53) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL4401124 | 0.89 | KLK5 (0.51) | KLK5RENCTSSCTSLCTSB | |
| SCHEMBL31177486 | 0.87 | KLK5 (0.52) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL23921535 | 0.87 | KMT2A (0.53) | KLK5KMT2ARENATM | |
| SCHEMBL21554815 | 0.87 | KMT2A (0.53) | KLK5KMT2ARENATM | |
| SCHEMBL31177458 | 0.86 | REN (0.52) | KLK5L3MBTL1KMT2ARENCTSS | |
| SCHEMBL21554936 | 0.86 | REN (0.53) | L3MBTL1KMT2ARENCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |