Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 0.44 |
| ▸ | BCL2 | P10415 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198049 | 0.85 | ADORA2A (0.50) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL15177181 | 0.84 | MCL1 (0.58) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL28028179 | 0.84 | LTA4H (0.44) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL28834355 | 0.82 | MCL1 (0.41) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL29151801 | 0.82 | LTA4H (0.42) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| Bromide SCHEMBL28952170 | 0.81 | LTA4H (0.41) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL29151803 | 0.81 | MCL1 (0.40) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL29151807 | 0.81 | MCL1 (0.40) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| SCHEMBL14935514 | 0.81 | MCL1 (0.60) | MCL1BCL2KMT2AKDM4EALDH1A1 | |
| Bromide SCHEMBL28834308 | 0.80 | MCL1 (0.39) | MCL1BCL2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829488-B | A kind of support type α diimine metal complexes and its application in olefin polymerization | 天津工业大学 | 2017-03-01 | — | — | CN | disclosed |
| CN-104926686-B | A kind of alpha-diimine compound and comprise the metal complex of this compound, loaded article and its application | 河北工业大学 | 2016-11-09 | — | — | CN | disclosed |
| CN-104926686-A | Alpha-diimine compound, metal complex and load containing compound and application thereof | UNIV HEBEI TECHNOLOGY | 2015-09-23 | — | — | CN | disclosed |
| CN-104829488-A | Supported alpha-diimine metal complex, and its application in olefin polymerization | UNIV TIANJIN POLYTECHNIC | 2015-08-12 | — | — | CN | disclosed |