SCHEMBL28028232

SCHEMBL28028232

CN1CCN(CCn2cc3ccccc3c2C(=O)C=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.46
HRH3 Q9Y5N1 2/20 0.43
ERN1 O75460 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 3/20 0.42
HPGD P15428 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
RELA Q04206 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HTR7 P34969 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27997552 0.79 CREBBP (0.38) CNR1HPGDKDM4EALDH1A1LMNA
SCHEMBL27926249 0.79 PTPN1 (0.34) ERN1ALDH1A1
SCHEMBL27937758 0.77 HSD17B10 (0.33) CNR1ERN1MAPTHPGDKDM4E
SCHEMBL27670405 0.76 CNR2 (0.34) CNR1HRH3
SCHEMBL27951823 0.76 CNR2 (0.41) CNR1HRH3
SCHEMBL27799440 0.75 CNR2 (0.37) CNR1HRH3
SCHEMBL28826410 0.75 CNR2 (0.43) CNR1HRH3
SCHEMBL27612025 0.74 CNR1 (0.37) CNR1
SCHEMBL28028228 0.74 LMNA (0.37) HPGDNPC1KDM4EMEN1KMT2A
SCHEMBL28054209 0.73 USP2 (0.40) MAPTHPGDALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104884426-A Cinnamide derivative NIPPON ZOKI PHARMACEUCTICAL CO LTD 2015-09-02 CN disclosed