Pyridine

Pyridine

SCHEMBL28028534

O=S(=O)(O)c1c(S(=O)(=O)O)c2ccc3cccc4cc(S(=O)(=O)O)c(c1S(=O)(=O)O)c2c34.c1ccncc1

nearest known ligand 0.35

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 2/20 0.35
CYP1A2 P05177 6/20 0.35
ERBB2 P04626 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35
ACHE P22303 1/20 0.35
AHR P35869 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2D6 P10635 1/20 0.34
TTR P02766 1/20 0.34
FABP4 P15090 1/20 0.34
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
MAPK14 Q16539 1/20 0.34
NR4A1 P22736 1/20 0.33
HIF1A Q16665 3/20 0.32
HPGD P15428 2/20 0.32
CYP1A1 P04798 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304340 0.91 CYP1A2 (0.41) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL34463528 0.91 CYP1A2 (0.41) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL31030170 0.91 CYP1A2 (0.41) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL4752220 0.90 CYP1A2 (0.40) ALDH1A1MAPK1CYP1A2ERBB2FYN
Calcium SCHEMBL31296027 0.90 CYP1A2 (0.40) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL2455933 0.90 CYP1A2 (0.40) ALDH1A1MAPK1CYP1A2ERBB2FYN
Water SCHEMBL28838553 0.90 CYP1A2 (0.40) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL4309579 0.90 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL2455936 0.90 ALDH1A1 (0.42) ALDH1A1MAPK1CYP1A2ERBB2FYN
SCHEMBL3690633 0.80 CYP2D6 (0.43) ALDH1A1MAPK1CYP1A2ERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104962280-A Calixpyridine-pyrenetetrasulfonid acid tetrasodium salt supramolecular fluorescence sensor, and its application in ATP hydrolysis reaction UNIV TIANJIN NORMAL 2015-10-07 CN claimed
CN-106153589-A Cup pyridine Selective recognition method to acidic amino acid in neutral physiological ph aqueous solution 天津师范大学 2016-11-23 CN disclosed
CN-104962280-A Calixpyridine-pyrenetetrasulfonid acid tetrasodium salt supramolecular fluorescence sensor, and its application in ATP hydrolysis reaction UNIV TIANJIN NORMAL 2015-10-07 CN disclosed