Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769892 | 0.88 | CTDSP1 (0.44) | MAPTMAPK1HTTMETAP1CYP1A2 | |
| SCHEMBL29919808 | 0.86 | METAP1 (0.45) | L3MBTL1HTTMETAP1NPC1RAB9A | |
| SCHEMBL69347 | 0.86 | METAP1 (0.45) | L3MBTL1HTTMETAP1NPC1RAB9A | |
| SCHEMBL7410153 | 0.85 | METAP1 (0.41) | L3MBTL1HTTMETAP1NPC1RAB9A | |
| SCHEMBL16766552 | 0.85 | KDM4E (0.47) | MAPTHTTMETAP1CYP1A2NPC1 | |
| SCHEMBL2696598 | 0.83 | GRM5 (0.46) | HTTMETAP1RAB9ANAMPTKDM4E | |
| SCHEMBL7408740 | 0.83 | METAP1 (0.40) | L3MBTL1METAP1CYP3A4NPC1RAB9A | |
| SCHEMBL27703346 | 0.82 | METAP1 (0.44) | L3MBTL1METAP1CYP3A4NPC1RAB9A | |
| SCHEMBL2695265 | 0.81 | METAP1 (0.42) | METAP1NAMPTKDM4EALDH1A1HPGD | |
| SCHEMBL7419909 | 0.81 | METAP1 (0.39) | L3MBTL1METAP1CYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781256-B | 3,4 pairs of substitution oxazolidinone derivatives and its purposes as the inhibitor of calcium-activated potassium channel | 霍夫曼-拉罗奇有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-104781256-A | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel | HOFFMANN LA ROCHE | 2015-07-15 | — | — | CN | disclosed |