Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545170 | 0.84 | KCNH2 (0.44) | KCNH2SMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL11656343 | 0.81 | ESR1 (0.36) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL11661897 | 0.81 | ESR1 (0.36) | KCNH2KDM4EALDH1A1 | |
| SCHEMBL6380984 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL10494779 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL442769 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL6559348 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL7458957 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL9386106 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL2549406 | 0.81 | KCNH2 (0.49) | KCNH2SMN1; SMN2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218356-A | PPAR gamma selective adjusting control agent and its production and use | SHANGHAI INST MATERIA MEDICA | 2016-01-06 | — | — | CN | disclosed |