Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029228 | 0.93 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28028867 | 0.86 | PIK3CD (0.46) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28028902 | 0.83 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL300833 | 0.83 | PIK3CD (0.68) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28028873 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28029232 | 0.83 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28029206 | 0.83 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28029211 | 0.82 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28029227 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28029229 | 0.81 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870998-A | Inhibition of phosphorylation of PRAS40, GSK 3-beta or P70S6K1 as a marker of TOR kinase inhibitory activity | SIGNAL PHARM LLC | 2015-08-26 | — | — | CN | disclosed |