Acenaphthene

Acenaphthene

SCHEMBL28028969

c1cc2c3c(cccc3c1)CC2.c1cc2c3c(cccc3c1)CC2.c1cc2c3c(cccc3c1)CC2

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
CYP3A4 P08684 3/20 0.57
HSD17B10 Q99714 7/20 0.56
LMNA P02545 2/20 0.56
ALDH1A1 P00352 12/20 0.50
HPGD P15428 9/20 0.50
CYP1A2 P05177 3/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
KDM4E B2RXH2 5/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
TYMS P04818 1/20 0.41
CYP2C19 P33261 1/20 0.41
ATM Q13315 2/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acenaphthene SCHEMBL3416108 1.00 TSHR (0.57) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL29386207 1.00 TSHR (0.57) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL598252 1.00 TSHR (0.57) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL1162573 1.00 TSHR (0.57) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL9017 1.00 TSHR (0.57) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL29182301 0.97 TSHR (0.55) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL27885324 0.97 TSHR (0.55) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL30729939 0.97 TSHR (0.55) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL29586283 0.97 TSHR (0.55) TSHRCYP3A4HSD17B10LMNAALDH1A1
Acenaphthene SCHEMBL27601829 0.97 TSHR (0.55) TSHRCYP3A4HSD17B10LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104772328-B A kind of biological prosthetic oil hydrocarbon compound contaminated soil method and application 黄晓东 2018-08-10 CN disclosed
CN-108339024-A A kind of method of harmful substance in removal plant extracts 湖南诺泽生物科技有限公司 2018-07-31 CN disclosed
CN-104772328-A Method for biologically repairing soil polluted by petroleum hydrocarbon compounds and application HUANG XIAODONG 2015-07-15 CN disclosed