Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.50 |
| ▸ | HPGD | P15428 | 9/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acenaphthene SCHEMBL3416108 | 1.00 | TSHR (0.57) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL28028969 | 1.00 | TSHR (0.57) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL29386207 | 1.00 | TSHR (0.57) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL1162573 | 1.00 | TSHR (0.57) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL9017 | 1.00 | TSHR (0.57) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL29182301 | 0.97 | TSHR (0.55) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL27885324 | 0.97 | TSHR (0.55) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL30729939 | 0.97 | TSHR (0.55) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL29586283 | 0.97 | TSHR (0.55) | TSHRCYP3A4HSD17B10LMNAALDH1A1 | |
| Acenaphthene SCHEMBL27601829 | 0.97 | TSHR (0.55) | TSHRCYP3A4HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109813827-A | Study the device and test method that persistence organic pollutant Low Temperature Solid-Phase generates | 中国科学院大连化学物理研究所 | 2019-05-28 | — | — | CN | claimed |
| CN-104558361-B | Preparation method and application of hydrophilic polyaromatic hydrocarbon molecularly imprinted solid phase extraction filler | 中国科学院烟台海岸带研究所 | 2017-05-17 | — | — | CN | claimed |
| CN-104558361-A | Preparation method and application of hydrophilic polyaromatic hydrocarbon molecularly imprinted solid phase extraction filler | YANTAI INST COASTAL ZONE RES CAS | 2015-04-29 | — | — | CN | claimed |
| CN-106862262-A | A kind of soil biochemistry complex repairation agent and preparation method and application | 四川大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-104672954-B | Low polycyclic aromatic hydrocarbon content furnace black production method and colour carbon black product | 安徽黑钰颜料新材料有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-104558361-B | Preparation method and application of hydrophilic polyaromatic hydrocarbon molecularly imprinted solid phase extraction filler | 中国科学院烟台海岸带研究所 | 2017-05-17 | — | — | CN | disclosed |
| CN-106645455-A | Gas chromatography tandem mass spectrometry detection method for 18 polycyclic aromatic hydrocarbons in plastic products | 中华人民共和国台州出入境检验检疫局 | 2017-05-10 | — | — | CN | disclosed |
| CN-105733636-A | Heat integration distillation deep processing method and device of absorber oil | 天津中科拓新科技有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-104672954-A | Production method of furnace carbon black with low polyaromatic hydrocarbon content and pigment carbon black product thereof | BLACK DIAMOND MATERIAL SCIENCE CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-104558361-A | Preparation method and application of hydrophilic polyaromatic hydrocarbon molecularly imprinted solid phase extraction filler | YANTAI INST COASTAL ZONE RES CAS | 2015-04-29 | — | — | CN | disclosed |
| CN-102405200-B | Novel organic compound, light-emitting device, and image display apparatus | CANON KK | 2014-12-10 | — | — | CN | disclosed |
| CN-1561872-A | Method for producing diacetate fiber tows of chitosan modified cigarette | UNIV JIANGNAN (CN) | 2005-01-12 | — | — | CN | disclosed |
| US-20040214844-A1 | N4-acylcytosine nucleosides for treatment of viral infections | GILEAD PHARMASSET LLC | 2004-10-28 | — | — | US | disclosed |
| EP-1461041-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | Pharmasset Ltd. (BB) | 2004-09-29 | — | — | EP | disclosed |
| US-20030176319-A1 | For therapy and prophylaxis of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts | GILEAD PHARMASSET LLC | 2003-09-18 | — | — | US | disclosed |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | disclosed |
| WO-2003063771-A2 | N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS | PHARMASSET LTD. (BB) | 2003-08-07 | — | — | WO | disclosed |
| WO-2003051298-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051306-A2 | N4-ACYLCYTOSINE-1,3-DIOXOLANE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS | PHARMASSET LTD. (BB) | 2003-06-26 | — | — | WO | disclosed |
| US-5600958-A | Shipper | HENNING STEVE (US) | 1997-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176319-A1 | For therapy and prophylaxis of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts | ENTPD5, CDA, ADA | TSHR 4374/4885CYP3A4 740/4885HSD17B10 631/4885 |
| US-20040214844-A1 | N4-acylcytosine nucleosides for treatment of viral infections | ENTPD5, DUT, PNP | TSHR 4420/4885CYP3A4 826/4885HSD17B10 1057/4885 |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | DERA, DPYD, DHPS | TSHR 3766/4885CYP3A4 1525/4885HSD17B10 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.