SCHEMBL28029482

SCHEMBL28029482

[CH2]CCNC(=O)C(C)(C)Br

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
EPHX1 P07099 1/20 0.31
DRD2 P14416 2/20 0.31
DRD4 P21917 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649228 0.85 POLB (0.39) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL1472130 0.81 POLB (0.44) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL4496590 0.79 CNR1 (0.42) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL16268506 0.77 POLB (0.38) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL3711677 0.77 MAOB (0.37) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL19736642 0.76 POLB (0.33) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL13121178 0.76 CA12 (0.35) POLBALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL17669630 0.76 ECE1 (0.42) POLBKMT2A
SCHEMBL14307207 0.76 TSHR (0.37) POLBALDH1A1SMN1; SMN2TP53
SCHEMBL22351756 0.76 EPHX1 (0.52) POLBALDH1A1SMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114113287-A Serum protein preparation method and serum proteome mass spectrum detection method 北京青莲百奥生物科技有限公司 2022-03-01 CN disclosed
CN-105727911-A Glycidyl-methacrylate-grafted and diethylamine-modified agarose gel chromatographic medium, method for preparing same and application of glycidyl-methacrylate-grafted and diethylamine-modified agarose gel chromatographic medium 天津大学 2016-07-06 CN disclosed
CN-105001376-A Method for preparing high-capacity protein chromatographic medium through atom transfer radical polymerization UNIV TIANJIN 2015-10-28 CN disclosed
CN-101959972-A Surface modification of metal oxide nanoparticles SPARKXIS B V 2011-01-26 CN disclosed