Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268506 | 0.91 | POLB (0.38) | POLBALDH1A1SMN1; SMN2USP2TSHR | |
| SCHEMBL19736642 | 0.89 | POLB (0.33) | POLBALDH1A1SMN1; SMN2USP2TSHR | |
| SCHEMBL4496590 | 0.87 | CNR1 (0.42) | POLBALDH1A1SMN1; SMN2USP2TSHR | |
| SCHEMBL3711677 | 0.85 | MAOB (0.37) | POLBALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL13121178 | 0.84 | CA12 (0.35) | POLBALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL14307207 | 0.84 | TSHR (0.37) | POLBALDH1A1SMN1; SMN2TSHRTP53 | |
| Hydrochloric Acid SCHEMBL9983100 | 0.84 | MEN1 (0.39) | POLBALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL17669630 | 0.84 | ECE1 (0.42) | POLBTSHRKMT2ALMNA | |
| SCHEMBL22351756 | 0.84 | EPHX1 (0.52) | POLBALDH1A1SMN1; SMN2TSHREPHX1 | |
| SCHEMBL14052421 | 0.84 | PTGS1 (0.47) | POLBALDH1A1SMN1; SMN2CA3CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119710-B2 | Filled rubber compounds with improved processability | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | CIBA CORPORATION | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317778-A1 | Filled Rubber Compounds with Improved Processability | RER1, RIF1, REV1 | POLB 569/4885ALDH1A1 1605/4885SMN1; SMN2 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.