⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553066 | 0.78 | — | — | |
| SCHEMBL869031 | 0.78 | — | — | |
| SCHEMBL7710594 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7710602 | 0.76 | — | — | |
| SCHEMBL6720023 | 0.74 | — | — | |
| SCHEMBL7710928 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL10873027 | 0.74 | HAO1 (0.34) | — | |
| SCHEMBL1882239 | 0.72 | — | — | |
| SCHEMBL5898819 | 0.72 | — | — | |
| Ethylene Glycol SCHEMBL869611 | 0.72 | SLC22A6 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108743588-A | The method for treating gefitinib resistant cancer | 综合医院公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108421044-A | The method for treating gefitinib resistant cancer | 综合医院公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-107496932-A | XTEN conjugate compositions and its method of manufacture | 阿穆尼克斯运营公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-102782159-B | Compositions and methods for sequencing nucleic acids | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-101918030-B | The compositions of VEGF antibody and method | PEREGRINE PHARMACEUTICALS, INC. (US) | 2015-10-14 | — | — | CN | disclosed |