Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825174 | 0.85 | MEN1 (0.43) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL6095770 | 0.85 | MEN1 (0.43) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL31373870 | 0.81 | NOTUM (0.44) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL20738520 | 0.81 | NOTUM (0.44) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL24926039 | 0.77 | CES1 (0.46) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29338286 | 0.76 | MEN1 (0.37) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL28247397 | 0.76 | RAB9A (0.38) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL30900336 | 0.74 | PIM1 (0.42) | — | |
| SCHEMBL11376710 | 0.72 | ASAH1 (0.49) | POLBLMNAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29111703 | 0.72 | PTGDR2 (0.36) | MEN1KMT2APOLBPTGDR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237460-B | 2-acyl group replaces the one-step method for synthesizing of 1-isoindolinone compounds | 陕西师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105237460-A | One-step synthetic method for 2-acyl substituted isoindoline-1-ketone compounds | UNIV SHAANXI NORMAL | 2016-01-13 | — | — | CN | disclosed |