Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739070 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13741151 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL28030137 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13739069 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13741149 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13739068 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13739858 | 0.93 | HTR6 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 | |
| SCHEMBL13738196 | 0.93 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28822095 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15668028 | 0.76 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3CYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918615-B | The method for treating hepatopathy | 扎夫根股份有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-103764641-B | The tricyclic compound of fractional saturation and preparation and application thereof | 扎夫根股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-104918615-A | Methods of treating liver diseases | ZAFGEN INC | 2015-09-16 | — | — | CN | disclosed |