SCHEMBL28030201

SCHEMBL28030201

N#Cc1c(Cc2cccc(N)c2)cccc1Cc1cccc(N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
MAOA P21397 2/20 0.44
CYP19A1 P11511 1/20 0.43
AS3MT Q9HBK9 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MPO P05164 1/20 0.38
CYP3A4 P08684 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
MDM4 O15151 1/20 0.36
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
PARP1 P09874 1/20 0.35
ANPEP P15144 1/20 0.35
KDM4E B2RXH2 1/20 0.35
IKBKB O14920 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12808652 0.83 MAOB (0.41) MAOBMAOACYP19A1AS3MTMPO
SCHEMBL28030199 0.81 CYP3A4 (0.48) MAOBMAOACYP19A1CYP3A4MDM4
SCHEMBL486858 0.81 MAOB (0.59) MAOBMAOACYP19A1CA1CA2
SCHEMBL49433 0.76 MAOB (0.62) MAOBMAOACYP19A1CA1CA2
SCHEMBL30583096 0.76 MAOB (0.62) MAOBMAOACYP19A1CA1CA2
SCHEMBL841645 0.76 MAOB (0.53) MAOBMAOACYP19A1CA1CA2
SCHEMBL28158901 0.74 MAOB (0.52) MAOBMAOACYP19A1CA1CA2
SCHEMBL9719335 0.74 MAOB (0.60) MAOBMAOACYP19A1CA1CA2
Hydrochloric Acid SCHEMBL10936113 0.74 MAOB (0.64) MAOBMAOACYP19A1CA1CA2
Hydrochloric Acid SCHEMBL8644377 0.74 MAOB (0.64) MAOBMAOACYP19A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104927072-A Solvent-resistant polyimide thin film with low thermal expansion coefficient and preparation method for polyimide thin film LU AN CITY DUERBANG INSULATION MATERIALS CO LTD 2015-09-23 CN claimed
CN-104927072-B A kind of Kapton and preparation method thereof of solvent resistant low thermal coefficient of expansion 六安市杜尔邦绝缘材料有限公司 2019-05-14 CN disclosed
CN-104927072-A Solvent-resistant polyimide thin film with low thermal expansion coefficient and preparation method for polyimide thin film LU AN CITY DUERBANG INSULATION MATERIALS CO LTD 2015-09-23 CN disclosed