Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404173 | 0.81 | TDO2 (0.46) | MAP4K4TDO2KMT2A | |
| SCHEMBL9950905 | 0.80 | ADORA2A (0.43) | MAP4K4CYP1A2KCNH2MINK1TNIK | |
| SCHEMBL19835835 | 0.77 | MALT1 (0.55) | MALT1 | |
| SCHEMBL19835672 | 0.75 | MALT1 (0.53) | MALT1 | |
| SCHEMBL8997577 | 0.75 | MALT1 (0.56) | MALT1 | |
| SCHEMBL19835323 | 0.75 | MALT1 (0.50) | MAP4K4CYP1A2KCNH2MINK1TNIK | |
| SCHEMBL28279863 | 0.75 | MALT1 (0.53) | MALT1 | |
| SCHEMBL28280903 | 0.75 | MALT1 (0.53) | MALT1 | |
| SCHEMBL31181608 | 0.74 | ADORA2A (0.58) | TDO2PTGS2PTGS1 | |
| SCHEMBL21098838 | 0.74 | MALT1 (0.52) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903308-A | Piperidinylcarbazole as antimalarial | MERCK PATENT GMBH | 2015-09-09 | — | — | CN | disclosed |