Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17374976 | 0.93 | MAPT (0.46) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL28030111 | 0.79 | HSD17B10 (0.47) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL16307679 | 0.79 | CYP1A2 (0.48) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL3829978 | 0.77 | TSHR (0.56) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL14010958 | 0.76 | MAPT (0.53) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL30095409 | 0.76 | MAPT (0.53) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL28338203 | 0.75 | TSHR (0.54) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL27981594 | 0.75 | ALDH1A1 (0.46) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL28122579 | 0.74 | TSHR (0.59) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL5778139 | 0.74 | SNCA (0.50) | MAPTCYP3A4NOS1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017152-B | Preparation method of 3-chloro-6-nitroisoquinoline or 3-bromine-6-nitroisoquinoline | 北京六合宁远科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105017152-B | Preparation method of 3-chloro-6-nitroisoquinoline or 3-bromine-6-nitroisoquinoline | 北京六合宁远科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105017152-A | Preparation method of 3-chloro(bromo)-6-nitroisoquinoline | BEIJING LIUHE NINGYUAN TECHNOLOGY CO LTD | 2015-11-04 | — | — | CN | disclosed |