SCHEMBL28030677

SCHEMBL28030677

NC(=O)c1c(Cl)cc([N+](=O)[O-])cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GPR35 Q9HC97 1/20 0.52
HSD17B10 Q99714 1/20 0.48
LMNA P02545 2/20 0.47
TSHR P16473 2/20 0.47
GAA P10253 1/20 0.43
NR1H4 Q96RI1 1/20 0.43
CASP1 P29466 1/20 0.42
CYP19A1 P11511 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5787593 0.82 ALDH1A1 (0.59) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35
SCHEMBL6497182 0.82 ALDH1A1 (0.59) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35
SCHEMBL28352192 0.78 ALDH1A1 (0.68) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35
SCHEMBL16237265 0.77 KMT2A (0.61) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35
SCHEMBL11649113 0.76 ALDH1A1 (0.53) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35
Aklomide SCHEMBL29637033 0.76 KMT2A (1.00) KMT2AALDH1A1CYP3A4SMN1; SMN2HSD17B10
SCHEMBL5787676 0.76 NR1H4 (0.52) KMT2AALDH1A1SMN1; SMN2GPR35HSD17B10
SCHEMBL9737315 0.76 CA1 (0.67) KMT2AALDH1A1SMN1; SMN2GPR35HSD17B10
Aklomide SCHEMBL328368 0.76 KMT2A (1.00) KMT2AALDH1A1CYP3A4SMN1; SMN2HSD17B10
SCHEMBL3398819 0.76 TSHR (0.47) KMT2AALDH1A1CYP3A4SMN1; SMN2GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385185-A Clean preparation method of weakly alkaline arylamine azo disperse dye UNIV DALIAN TECH 2016-03-09 CN disclosed
CN-105038316-A Heterocyclic azo disperse dye and preparation method thereof UNIV DALIAN TECH 2015-11-11 CN disclosed