Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 19/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.81 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.81 |
| ▸ | USP7 | Q93009 | 1/20 | 0.68 |
| ▸ | PDE5A | O76074 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508267 | 0.90 | MAP4K4 (1.00) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL2976390 | 0.82 | MAP4K4 (0.62) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL971373 | 0.80 | MAP4K4 (0.80) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL10017414 | 0.79 | MAP4K4 (0.58) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL313209 | 0.79 | MAP4K4 (0.58) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL18263118 | 0.79 | MAP4K4 (0.58) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL1346652 | 0.79 | MAP4K4 (0.58) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL11011540 | 0.75 | ALDH1A1 (0.56) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL10017415 | 0.75 | MAP4K4 (0.54) | MAP4K4KCNH2MINK1CYP1A2TNIK | |
| SCHEMBL21241745 | 0.75 | MAP4K4 (0.54) | MAP4K4KCNH2MINK1CYP1A2TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903308-A | Piperidinylcarbazole as antimalarial | MERCK PATENT GMBH | 2015-09-09 | — | — | CN | disclosed |